After restoration, the manor palace reopened to visitors in 2021. Historical records of the manor site date back to the 16th century, when it was owned by Lithuanian Tatars. Later the manor belonged to Paweł Stefan Sapieha, Master of the Horse of the Grand Duke. At the beginning of the 17th century the owner of the manor was Tomasz Sapieha (1598–1646), Voivode of Navahrudak. The later fate of the manor (until as late as the end of the 18th century) is unknown. At the turn of the 18th and 19th centuries the manor passed to the Dąbrowski family. The first owner from this family was Józef Dąbrowski. The manor was inherited from him by his son Ludwik, Marshal of the Nobility of Trakai County. After 1850 Trakų Vokė Manor was bought from Ludwik Dąbrowski or his son Władysław Ksawery Dąbrowski by Count Jan Tyszkiewicz, Marshal of the Nobility of Vilnius Governorate. After his death the manor passed to his younger son, also named Jan. After the early deaths of Jan Tyszkiewicz and his wife Elżbieta Krasińska, the entire estate went to their young children, who were growing up in Poland. Until 1914 the manor was lived in only in summer. On coming of age, Jan Michał Tyszkiewicz inherited the manor. After his untimely death, three underage children became the heirs, but with the outbreak of the Second World War this no longer mattered. In 1939 the Lithuanian army was stationed at the manor, and during the Second World War Dutch colonists lived here. After the war the palace was a villa of the Council of Ministers of the Lithuanian SSR, and later it housed an agricultural institute. Almost all the surviving buildings were built while the Tyszkiewicz family owned the manor. This was the manor's heyday.